Probably not. The taxable element is processed as pay for that period through your payroll and so if it puts you over your standard rate cut off point for that pay period, then the 41% rate will apply.
However, if this happens, you will be entitled to some tax back. You can submit p50s every month (once you are unemployed for a month) and if some of it still remains taxed at the higher rate you should apply for top slicing relief after the year end.