You might be on a sticky wicket if the 285k valuation report is for the bank. Are you getting a mortgage? The bank will only lend the appropriate %age based on the valuer's report, not the sale price. That's your main argument IMO & one the vendor may listen to.
My view is that it would be easy to see if windows need replacing just by your own viewing. Heating, plumbing and electrics are not so obvious but it may have reasonably been clear to you by e.g. the age of the house that you should have been aware that they needed upgrading prior to the survey. If that's the case, I can sort of understand why the vendor is being sticky about it, particularly seeing you negotiated a reduced price from the outset (it's just human nature - the vendor may think they have given as much as they can/want)
If the matters (or the extent of them) brought up in the survey are a surprise to you, then it's easier to argue for a reduction in price. If you can also provide the vendor with an estimate of what it would cost to replace/upgrade and the timeline you have been advised to do it in, that will also bolster your case.
I think your biggest issue is your mortgage approval, so I'd look at that as soon as you can.