My husband & I did the whole 'road-trip' thing for our honeymoon last June. It was the best trip ever.
We decided that we wanted to do Las Vegas & San Francisco (we were undecided about LA). So, we booked our flights and first few nights accom in Las Vegas... nothing else was booked or planned. Instead, when we go away, we always bring a laptop and book into hotels that offer internet connection - so we book our trip on the go.
In the end, we ended up driving from Las Vegas to LA... then drove up the Pacific Highway (Hwy 1) to San Francisco - this was a fantastic drive! Driving on some parts of the road was a little scary for me (hairpins and cliffs...

)... I was more than happy to hand the driving back over to hubby!
Between Carpentaria & Santa Cruz, on the Highway, there is a fabulous restaurant called
Nepenthe. Built into the Cliff Side with incredible views of the Pacific Coast, it was designed by a student of Frank Lloyd Wright. The food was good, and although it was expensive, it didn’t seem to matter. We’ve eaten in hundreds of restaurants, but there’s something about eating in a place like this that stays with you. You don’t forget it.
When we got to San Fran, we stayed there for a 2 days, before flying back to Vegas, homeward bound. In all we drove 1000 miles - at our own pace. We might have got a bit more in, had we planned every detail of the trip - but that's not what the two of us are about... or what we wanted for this trip.
All in all, it was a fantastic trip... planning it OURSELVES, made each stage of the trip more memorable - if we didn't feel like doing something on a particular day, we didn't. If, on the otherhand, you go through a travel agent, your compelled to do everything set out... to get your money's worth...which can be exhausting - and that's not what a honeymoon is about. I highly recommend you doing things yourselves.