Ok, I wasn't sure from your first post if she was going back on Illness Benefit.
You can claim for your wife as a Qualified Adult (Adult Dependant) on your Jobseeker's Benefit, which will increase your payment. You should contact your local office (where you sign on) as soon as possible, and bring any letters that your wife received regarding the medical & having to stop the CE scheme.
As the increase you wiill get is less than what she was getting on the CE scheme (Qualified Adult rate is currently €135.60 pw), you should ask for your Mortgage Interest Supplement to be reviewed.
Your wife could apply for Disability Allowance if she is likely to be ill long-term. This is a means-tested payment, not PRSI contribution based.