The question you need to ask yourself, is what you want to do with your money.
Is the goal to buy a property, take time off, retire early, travel, settle down.
You are in a very good position, but what you should do with what you have saved will depend on what your plans are.
Regarding property, you are in a very good position to call the shots, regarding what you want, and where you want it. Given your salary and savings, you could easily get into a situation where you are a slave to your mortgage over the next 20 or more years, buy buying a bigger house than you need, or you can buy something sensible, and have most of your money at work for you - given the price range you mention, and assuming a 50/50 split, it seems like a sensible move.
What level of risk are you comfortable with. What sort of gains are you looking for and what sort of losses would you be willing to take.
Once you figure out your goals, you can make it happen. You just need to prioritize what exactly it is you are shooting for, before proper advice can be given.
Regading equity and funds, i'd steer clear of irish based equity houses, who seem better at charging fees than managing. The tax implications of an offshore account should be investigated. Given the weak dollar, moving some of you money to an american money manager might be an avenue worth persuing, since the fees are lower and the quality of management higher.
Let us know what your thoughs on what direction you wish to move are, and we can go from there..